Home » NEW & IMPROVED Formulation ofL.E.T. Topical Gels and Solution

L.E.T. (Lidocaine, Epinephrine, Tetracaine) Gels & Solution — Now with Extended BUD

Name: NEW & IMPROVED Formulation of L.E.T. Topical Gels and Solution
Brand: QuVa Pharma

Consider adding QuVa L.E.T. products to your LET kits in the OR and your L.E.T. kits in your ED.

To place an order,

CLICK HERE.

L.E.T. (Lidocaine, Epinephrine, Tetracaine) Gels & Solution — Now with Extended BUD

A solution of lidocaine, epinephrine and tetracaine (L.E.T) is a topical anesthetic typically used in emergency rooms, pediatric practices and other urgent care settings. The most common application of L.E.T is to apply it to open wounds before suturing them1. QuVa dispenses L.E.T in syringes with doses ranging from 1.5 to 3.0 mL.

QuVa’s new, proprietary process and formulation* improves our L.E.T. gels and solution:

• 5-6 months shelf life — Increasing BUD reduces risk of wastage from expired medication

• Room temperature storage to facilitate direct storage in your ED Med Dispensing Cabinets

• 3 viscosities to cover a broad range of application needs

• Improved viscosity of the Thick Gel provides better adherence at application site

• Contains highly-effective antimicrobial preservatives

• Ready-to-administer — no weighing, mixing or stirring

• Patent pending formulation

Product #

Product Description

Product
Source

BUD
(DaYS)

Case
Quantity

70092161144

L.E.T. (Lidocaine, Epinephrine, Tetracaine) Gel 3 ml fill, 5 ml Topical Syringe

Non Sterile

180

70092161243

L.E.T. (Lidocaine, Epinephrine, Tetracaine) Thick Gel 1.5 ml fill, 3 ml Topical Syringe

Non Sterile

150

70092165844

L.E.T. (Lidocaine, Epinephrine, Tetracaine) Solution 3 ml fill, 5 ml Topical Syringe

Non Sterile

180

*Patent Pending

L.E.T. Formulation

A typical formulation of LET contains 4,000 mg lidocaine, 180 mg epinephrine bitartrate and 500 mg tetracaine. The epinephrine bitartrate component consists of 55 percent epinephrine and 45 percent bitartrate. This formulation also includes 75 mg sodium metabisulfite and enough sterile water to achieve a total volume of 100 mL². Lidocaine and tetracaine are both topical anesthetics, while the primary purpose of epinephrine bitartrate is to control superficial bleeding.

History

L.E.T has largely replaced the older formulation of tetracaine, adrenaline and cocaine (TAC), primarily due to cocaine’s high potential for dependency. A 1995 study published in Annals of Emergency Medicine showed no statistical difference in anesthetic effect between TAC and L.E.T, while eliminating the problematic use of cocaine³.

Benefits

QuVa’s proprietary process and patent pending formulation provides our L.E.T products with a range of benefits. The different viscosities allow them to cover a range of application needs. For example, the thick gel provides better adherence at the application site. The longer BUDs reduce the risk of wastage due to expired medication.

Our LET products are ready to administer, so they don’t require weighing, mixing or stirring. They can also be stored at room temperature, so you can keep them in an ED med dispensing cabinet. All three of QuVa’s products provide L.E.T in topical syringes, with 10 syringes per case.

Scale & Capacity to Deliver

QuVa has the capacity to deliver on a large scale, even during shortages. Our 503B cGMP quality management system (QMS) has a proven record of FDA compliance and resiliency. We also have four state-of- the-art facilities with a total area of 300,000 square feet. We are also licensed to ship to all 50 states.

Additional Capabilities

QuVa offers a full portfolio of sterile-to-sterile medications in the following formulations:

Bags (bulk and IV)
CADD®
PCA vials
Syringes (monoject and topical)

Our Kit Check® products use RFID to reduce the risk of misidentification. We also offer complimentary pharmacy solutions consulting services.

Therapeutic Classes

QuVa’s products include the following therapeutic classes:

Anesthesia & OR
Anti-Infective
Cardiovascular
General Medicine
Labor & Delivery
Pain Management

Place an Order

To place an order with QuVa, visit Portal.QuVaPharma.com. Please contact your sales account manager for questions about your order or general product information. You can also contact our customer service department by calling 888.339.0874 or sending a message to Customer.Service@QuV.aPharma.com.

To become a new customer, set up a profile at quvapharma.com/customerproﬁle. You can view our comprehensive product portfolio by requesting a full product catalog at www.QuVaPharma.com/products.

A partnership with QuVa Pharma helps provide you with a resilient, reliable supply of sterile injectable drugs.

1. https://www.aafp.org/afp/2017/0515/p628.html

2. https://www.pharmacytimes.com/view/2003-07-7309

3. https://pubmed.ncbi.nlm.nih.gov/7832348/